Yangtzeconus priscus-Archaeospira ornata, an important earliest Cambrian benthonic Assemblage of the Yangtze micromolluscan fauna, occurs mainly in the Lower Cambrian Zhongyicun and Dahai Members of the Yuhucun Formation in E Yunnan, the Tianzhushan Member (=Huangshandong Member) of the Dengying Formation in W Hubei and the Maidiping Member of the Hungchunping Formation in C Sichuan, China. About 90% of the genera of this Assemblage are unknown from the Nemakit-Daldynian and Tommotian molluscan Assemblages of the Siberian Platform, Russia. About 90% of the Siberian molluscan genera do not occur in the Zhongyicun and Dahai Members in the Meishucun section and in the corresponding beds of the Yangtze Platform, because the Tommotian molluscan Assemblage is characterizedly abundant archaeocyathids. It is clearly indicated that the Yangtze and Siberian molluscan Assemblages represent different bio- and lithofacies and ages. The age of the pre-trilobitic Yangtzeconus priscus-Archaeospira ornata Assemblage is older than that of the Nemakit-Daldynian and Tommotian molluscan Assemblages and referable to the Earliest Cambrian. Two new genera Mcnamaraconus and Zhangwentangoconus are herein proposed.