This paper mainly discusses the timing of the Karakorum strike-slip fault, and gives a brief introduction of its structures, offset, and deformational style. This fault strikes NNW-SSE. Asymmetrical folds, stretching lineation, S-C fabrics, feldspar and quartz σ-porphyroclasts, domino structure, shear cleavages and faults in the fault zone are products of tectonic movements. They all indicate a dextral slip sense of faulting. Mylonitic bands are widely developed along this fault. Phengite appears, indicating rather high deformational pressure. Geochronological data indicate that the Karakorum strike-slip faulting occurred from 6.88±0.36 to 8.75±0.25 Ma. The cumulative displacement from Muztag Ata to Muji is about 135 km.