The granitoids of the continental crust transformation series in South China may be divided into threetypes: (1) synorogenic migmatic and magmatic type. (2) anorogenic continental crust anatexis type, and (3)syncollision type. Based on the results of Sr and Nd isotopic determinations, the source material compositionof the three types of granitoids is calculated with crust-mantle binary mixing simulation. The calculations indi-cate that the granitoids of the first type consist of 78.6-89.7% upper crust endmember materials and15.0-10.3% depleted mantle endmember materials, the granitoids of the second type are composed of 63.7%upper crust endmember materials and 36.3% depleted mantle endmember materials, and those of the third type100% upper crust endmember materials. Hence. the source material composition of the granitoids of all thethree types is dominated by upper crust endmembers.