The study area, located in the central orogenic belt of the North China Craton, experienced the significant changes of several tectonic regimes and regional tectonic features during the MesozoicCenozoic era. The quantitative study of Paleoproterozoic granitic pluton in the northcentral part of Lüliang Mountain can directly and intuitively reveal the uplift and exhumation history of basement rocks. This will not only benefit understanding the evolution of the North China Craton but also provide evidence for the formation and evolution of energytype basins in neighboring areas. All the knowledge will deepen our understanding of resource preservation conditions in basins and thus provide basic evidence for resources development. Fission track thermochronology analysis of Paleoproterzoic granitic pluton reveals that initial uplift and denudation of Lüliang Mountain occurred in Late Cretaceous (88~77Ma) to Early Cenozoic (65~53Ma). Our study also shows that apatite was on the annealing zone, indicating that this area was in a short bury period but generally in uplift and denudation state. Fission track dating and thermalsimulation results indicate that since the Late Cretaceous, the uplift and cooling/exhumation history recorded by bedrocks in the northmiddle part of the Lüliang Mountain is spatiotemporally characterized by imbalance, with the central dome Guandishan granite intrusive pluton in uplift and exhumation in early Late Cretaceous. During Late Cretaceous, Yunzhongshan and Luyashan granite plutons in the north underwent tectonic uplifting and deformation due to compression. Since Early Cenozoic, fast uplifting (65~53Ma) of the plutons was the key change period between uplift and exhumation, which has some genetic link to the development of faulting on both eastern and western neighboring areas. Therefore, regional response in the central part of North China block may establish the development pattern of modern terrain for the northmiddle part of Lüliang Mountain.