Zircon LA-ICP-MS U-Pb dating and Hf isotopic compositions of intrusions from Zhunuo porphyry copper-gold-molybdenum and its geological significance. But the chronology and petrogenesis of intrusions are still unclear. According to research of Zircon U-Pb dating and Hf isotope study, we obtained the age of biotite granodiorite is 14.14±0.32Ma, 176Hf/177Hf, εHf(t), and two-stage age range from 0.282484 to 0.282750, -9.87~-0.49 and 1.13~1.73Ga respectively；The age of monzonitic granite is 14.05±0.31Ma, 176Hf/177Hf is 0.282633~0.282769, εHf(t) is -4.61~0.21, and two-stage age is 1.08~1.39Ga; The age of hornblende diorite porphyry is 14.10±0.29Ma, 176Hf/177Hf is 0.282607~0.282761，εHf(t) is -5.53~-0.07 with two-stage age between 1.10~1.45. The studies indicated that the ages of intrusions are similar to porphyry copper-molybdenum deposits at east of Gangdise metallogenic belt showing the similar, but Hf isotopic composition and older two stage model age(1.1~1.3Ga) are significantly different which show the more crustal contamination compared with Miocene porphyry copper-molybdenum deposits.