Vesignieite, Cu_3Ba(VO_4)_2(OH)_2, crystallizes in space group C_2 / m with a°=1.0270(2), b°=0.5911(1),c°=0.7711(2)nm and β=116.42(3)°. The intensity data were collected with the RIGAKU RASA-IISsingle-crystal four-circle diffractometer. The structure was determined by Patterson and Fourier methods andrefined by the least-square technique to a final R index of 0.051 for 614 independent diffraction points with|F? |>3σ|F?|. The crystal structure analysis shows that vesignieite has a layer structure parallel to (001). The powder diffraction lines were reindexed.