A new large-bodied theropod dinosaur, Datanglong guangxiensis gen. et sp. nov., was recovered from the Lower Cretaceous Xinlong Formation of the Datang Basin, Guangxi. It is unique in several features including: posteriormost dorsal vertebra with teardrop-shaped pneumatic foramen confined by enlarged pcdl, acpl and the centrum; posteriormost dorsal with well-developed, horizontal prpl; posteriormost dorsal with a parapophysis projecting more laterally than the diapophysis; brevis fossa shallow with short, ridge-like medial blade; and iliac pubic peduncle with posteroventrally expanded margin. Cladistic analysis supports the idea that this new taxon Datanglong guangxiensis is a primitive member of the Carcharodontosauria in possessing two unambiguous synapomorphies: large external pneumatic foramina and internal spaces present in the lateral surface of ilium, and a peg-and-socket ischiac articulation with the ilium. The presence of the new taxon from Guangxi further confirms that Carcharodontosauria were cosmopolitan large-bodied predators during the Early–mid Cretaceous.