The Hadamiao granodiorite, located on the northern margin of the North China platform and acting as the country rock of gold deposits in the Hadamiao region, was formed in the same age and similar tectonic settings with the Hadamiao gold deposit and the large-scale Bilihe gold deposit in the same area. By using the LA-ICP-MS method, the U-Pb age obtained is 267±1.3 Ma, which represents the crystallized age of the granodiorite, and that of the xenolithic zircon is 442.8±5 Ma. Base on the main elements, it exhibits the features of calc-alkaline to high-potassium calc-alkaline series, low silicon, and quasi-aluminous I-type granites, and with high magnesium (Mg#=0.45–0.57) and high sodium contents (Na2O/K2O=0.98–2.29). The SREE values (81.6–110.15 ppm) are relatively low, the fractionations between LREE and HREE are obvious, showing a right-inclined dispersion in the REE distribution diagram. Compared with the primitive mantle, the rock is relatively rich in LREE (La and Ce), LILE (K, Sr, and Th), and intensively depleted in HFSE (Ti, P, Nb and Ta). The ratios of Sr/Y and (La/Yb)N and the contents of Rb, Nb and Y are relatively low, the Sr values are high (436.35–567.26 ppm), and the Yb contents of most samples are low (1.25–1.8), which indicate the features of typical continental margin arc and adakitic rocks. According to the values of εNd(t) (?2.4 to +0.2) and ISr (0.7028–0.7083), and variations of the La/Sm ratios, the Hadamiao granodiorite was formed from mixing of the thickened molten lower crust and the mantle wedge substances. The rock was related to the southward subduction and accretion of the Paleo-Asia Ocean in the Late Paleozoic, being Late Paleozoic magma of the continental margin arc formed on the basement of the Early Paleozoic accretion complexes, and showing a trend of turning into adakitic rocks, which indicates their great metallogenic (Au) potential.