The new Qilian metallogenic belt was merged from the old Qilian belt and the Qaidam block which hosts several salt lakes. The belt covers through three provinces or autonomous regions (including Gansu, Qinghai and Inner Mongolia) with a total area of 11.4 km2. The belt is tectonically located at the conjunction area between the south margin of north China craton and Tethys tectonic belt, which a complex history of geological evolution and intensive magmatic activities. So the belt has favorable conditions of metallogeny and is an important ore deposit belt of potash, nickel and tungsten. Based on the previous studies, this study summarized the main geological characteristics and ore forming series of the Qilian metallogenic belt, defining the key mineral species and assessing mineral resources potential. Seven metallogenic series for sylvite, nicke and tungsten have been delineated, based on which two key prospecting areas (one in western Qaidam basin and the other in Jinchang of Gansu) and three average areas (one in Dadaorji, one in Xitieshan and one in Xialiugou). This has provided guidance evidence for geological investigation of this area.