Karst bauxite is the most important source of bauxite in China, accounting for more than 90% of the total resources, mainly distributed in the North China Craton and the southwest margin of the South China Block. In recent years, as a kind of strategic scarce mineral resource, the prospecting prediction of bauxite has become extremely urgent. This paper systematically summarizes the results of karst bauxite prospecting prediction and explores the optimal combination of prospecting prediction methods, so as to summarize the prospecting experience. By combing the examples and methods of geology, geophysics, geochemistry, remote sensing and artificial intelligence of geological big data to review the research results of karst bauxite prospecting and prediction in China, it is considered that geology and geophysics are still the most major methods for Chinese karstic bauxite prospecting prediction at present. In addition, the limitation of geochemical and remote sensing methods in searching for paleo-karst bauxite and their causes are analyzed, and the far-reaching significance of intelligent prospecting with geological big data is pointed out in the future.