To clarify the law of vertical distribution of oil and gas in the middle and upper part of oil and gas-bearing basins under the combination of fault-cap configurations.Methods: based on the research on the characteristics of the closed combination of fault-cap configurations and the vertical distribution of oil and gas transportation and gathering under them, a set of methods for the depiction of the vertical distribution of oil and gas transportation and gathering in the middle and upper part of oil and gas-bearing basins under the combination of fault-cap configurations are established through the superposition of the source rock-rooted fault transmission and gas transmission parts, and the source rock-rooted fault and the upper, middle, and lower part of regional mudstone caprock configurations that are closed and closed parts. It was used to delineate the longitudinal distribution of oil and gas transportation and gathering in the Gangdong fault of the Qikou sag in the Bohai Bay Basin and the regional mudstone caprock configuration combination of the middle part of the 1st member of the Shahejie Formation (Es1z), the 2nd member of Dongying Formation (Ed2) and the Minghuazhen Formation (Nm) in the lower sub-member of the 1st member of the Shahejie Formation (Es1x). The 3rd member of the Dongying Formation (Ed3) and the Neoproterozoic Guantao Formation (Ng). Results: The results show that the longitudinal distribution of oil and gas transport in the Es1z, Ed2and Nm under the combination of Gangdong fault and the Es1z, Ed2 and Nm is mainly in the east and west, and the longitudinal distribution of oil and gas transport in the Es1z, Ed2 and Nm under the combination of Gangdong fault and the Es1z, Ed2 and Nm are mainly in the east and west. The vertical distribution of oil and gas transport in Ed3 and Ng under the combination of the Gangdong fault and the regional mudstone caprock configurations of Es1z, Ed2 and Nm is mainly located in the middle of them. The vertical distribution of oil and gas transportation is relatively developed in Es1x under the combination of the Gangdong fault and the configuration of Es1z, Ed2, and Nm, which is favorable for oil and gas transportation and the formation of reservoirs. The vertical distribution of hydrocarbon transport in Ed3 and Ng under the configuration combination of the Gangdong fault with Es1z, Ed2 and Nm is relatively undeveloped, which is not conducive to the formation of reservoirs by hydrocarbon transport. This coincides with the current oil and gas distribution in Es1x, Ed3 and Ng at the Gangdong fault.Conclusions: This method is feasible to delineate the longitudinal distribution of oil and gas transport under the fault-cap configuration combination.