Bauxite is an advantageous mineral resource in the Guangxi region. The exploration work for alluvial bauxite in the area has reached a relatively high level, leaving limited potential for new discoveries. In contrast, the exploration of sedimentary bauxite is still in its initial stage, and its metallogenic rules and ore-seeking directions urgently require further systematic research. Based on the collection and comparison of data on sedimentary bauxite in the Yunnan-Guizhou region, and combined with recent exploration progress, this paper systematically discusses the metallogenic geological background, host strata, characteristics of aluminum-bearing rock series, orebody geological features, and ore quality of sedimentary bauxite in western Guangxi, aiming to provide guidance and reference for the exploration of sedimentary bauxite in the Guangxi region. Comparative research results show that the Heshan Formation (P3h) of the Upper Permian System in western Guangxi is widely distributed, with well-developed aluminum-bearing rock series, indicating good ore-seeking prospects and being the main target horizon for exploring sedimentary bauxite. The area has conditions to form thick funnel-shaped orebodies. Strengthening research on karst paleotopography and combining it with appropriate geophysical exploration methods can help discover such thick orebodies. However, due to inconspicuous leaching effects, the bauxite here is mainly in the form of bean-oolitic and dense ores, with relatively scarce earthy ores and lower ore grades.