Objectives: The Shesuo ophiolitic mélange is located in the middle-east segment of the Shiquanhe-Nam Co ophiolitic mélange zone. In order to clarify the petrogenesis, sedimentary environment and understand its geological significance of the siliceous rocks in the Shesuo ophilitic mélange. Furthermore, attempt to explore the tectonic attributes of the Shiquanhe-Nam Co ophiolitic mélange zone. Methods: In this paper, research on the siliceous rocks from the Shesuo ophiolitic mélange, including field work, petrology, as well as major-and trace-element analysis. Moreover, the petrogenesis and sedimentary environments of these siliceous rocks have also been analyzed. Results: The Shesuo siliceous rocks are exposed on the top of basalt, is purplish red or red color. The Shesuo siliceous rocks consist of three types: rich radiolarian siliceous rocks, interbedded radiolarian siliceous rocks, and rare radiolarian siliceous rocks. The geochemical characteristics of the rich radiolarian siliceous rocks reveal that they were biogenic siliceous rocks deposited at the continental magin which more farther from mainland in the subduction and reduction stage of the oceanic plate. interbedded radiolarian siliceous rock show that they were biogenic siliceous rock affected by the mid-oceanic ridge marginal hydrothermal plume, and were deposited in the oceanic basin. Rare radiolarian siliceous rocks reveal that it was hydrothermal siliceous rocks mey be deposited in the marginal area of the mid-oceanic ridge, far from the central rift valley. These siliceous rocks should have been deposited in different stages during the late Jurassic to early Cretaceous with the expansion of the oceanic crust. The subsequent geological structural activities such as the shortening of the Lhasa terrane, and the Qinghai-Tibet Plateau continuous uplift lead to the Shesuo siliceous rocks exposure within a limited area at present. Conclusions: Based on the research result of the Shiquanhe-Nam Co ophiolitic mélange zone, in this paper, we speculated that the Shesuo Meso-Tethy Ocean which located at the middle-east segment of the Shiquanhe-Nam Co Meso-Tethys Ocean was already has complete mid-oceanic ridge-oceanic basin-continental margin system, and the oceanic basin was mature and expansive relatively . It may be indicated that the Shiquanhe-Nam Co Meso-Tethys Ocean was an independent and new fromed ocean that emerged slightly later than the Bangongco-Nujiang Meso-Tethys Ocean.