Redox Sensitive Trace Metals and Bio- essential elements can deposit and formed special sedimentary mineral deposits in special sedimentary setting. Deep understanding the important elements geochemistry, relevant sedimentary mineral deposits and their spatial and temporal distribution characteristic, can improve our cognition between the old ocean evolution and sedimentary mineral deposits formation. Methods: In this paper, we reviewed relevant elements migrate and concentrated regulation, and redox discrimination methods which included pyrite morphology, and biological productivity and basin limitation discrimination methods. Then we centralized summarized Nanhuan to early Silurian sedimentary Mn, P, Ni—Mo—Co, V and U mineral deposit around Yangtze Block in genetic, distribution and the relation to lithofacies palaeogeography, under the background of global oxidation envent, glacial—interglacial envents, Rodinia supercontinent break up envent, metallogenic metal elements in the ocean accumulated during a long geology history. Results and Conclusions:So the sedimentary minerals in Yangtze Block margin from Neoproterozoic to early Paleozoic is the natural laboratory to ① research Redox Sensitive Trace Metals and Bio- essential elements action in different sedimentary environment, and ② metallogenic mechanism and the contribution of seawater—biology—hydrothermal fluid end members. At last, to solve the problems in sedimentary ore deposits study of Yangtze Block, we proposed solutions and future prospecting.