The Paleozoic and Mesozoic tectonic evolution of ocean—continentrealm in the northeast China is still controversial. The Permian—Early Jurassic multiple magmatic activities and homochromous ore deposits development in the central and eastern part of Heilongjiang Province provide crucial evidences to understand the ocean—continent transition process and metallogenic geological tectonic setting from Late Paleozoic to early Mesozoic in Northeast China. Based on the systematic summary of ophiolites, igneous rocks and ore deposits in the central and eastern part of Heilongjiang province, we recognize intraoceanic forearc basalt, Nbenriched basaltic andesite and an assemblage of tonodiorite, trondhjemite granodiorite (TTG). Themetallogenic and ocean—continent tectonic evolution in study area were divided into three stages of Permian, Early— Middle Triassic and Late Triassic—Early Jurassic. (1) The forearc basalt and Nbenriched basalt in the eastern margin of the Permian Jiamusi block recorded the initial westward subduction of the PaleoPacific slab. This westward subduction resulted in opening of the Mudanjiang ocean through a backarc was stretched between the Jiamusi block and the Songnen block. During this period, the wallrock granites of Permian gold deposits in the Jiamusi block are igneous (I)type granites that are related to the subduction of the PalaeoPacific. (2) The Mudanjiang ocean subducted westward in the Early—Middle Triassic, and formed porphyrytype molybdenum deposits related to the rollback of the Mudanjiang oceanic lithosphere subduction slab. (3) In the Late Triassic—Early Jurassic, the eastern margin of the Jiamusi block was continuously influenced by the paleoPacific subduction. Concurrently, the Mudanjiang ocean was closed during Late Triassic to Early Jurassic, and produced intense magmatic events caused by PaleoPacific subduction, syncollision, postcollision and late extension between the Songnen block and Jiamusi block. In this period, the porphyrytype molybdenum and skarntype multimetallogenic deposits were mainly formed in the Early Jurassic.