Geo- economics is a discipline that pays attention to the effectiveness of fund usage of geological research and mineral exploration,in purposes of more meaningful and more innovative achievements of scientific research, and more targeted in searching for ore minerals. The diamondiferous kimberlite is a kind of rock less distributed and hard to find in the world, but it is deeply studied in geological science and in exploration. From digesting global scientific research results, establishing diamond exploration target area, using indicator minerals to trace, eliminating interference rocks, and then using multiple means to determine the target, a set of effective steps of scientific research in purpose of ore prospecting is well established. In every step, we should consider the effectiveness of fund usage. In the paper, the authors put forward the Geo- economics, combined with the application in the whole process of looking for diamondiferous kimberlite and suggest that the Geo- economics should be run through in all aspects of scientific research and prospecting other mineral deposits. This paper also analyzes the prospective areas of diamond exploration in China.