Objectives: Previous research on the Qilinggranite is a part of the comprehensive research, so the research degree is low. This study used the elemental and isotopic geochemical methods,find out the source material characteristics, rock formation mechanism and tectonic environment, provide an important basis for the formation of uranium deposit in rock andthe formation and evolution of southern Zhuguangshan graniticcomposite.  Methods: The study collected the whole rock samples is fresh without alteration, the rock mineral identification under microscope, major element analysis using wet chemical methods, trace elements and REE analysis using Finnigan Element II ICP-MS determination, isotope analysis using MAT-262 thermal mass spectrometer. Results: The Qiling granite body in the main elements，with rich silicon （SiO2average of 72.24%），rich Al （A/CNK value averaged of 1.08），and high ratio of K2O/Na2O （average 1.86）；in the trace element，enriched in large ion elements（Rb, Th），Ba, Sr, Nb, P and Ti losses significantly；the rare earth elements significantly enriched，were rightwingtype distribution patterns，Eu losses significantly （δEu average of 0.28）；in isotopic terms，εNd(t)value is low（-10.3～-12.0）， ［n(87Sr)/n(86 Sr)］i high （0.71387～0.75424），Nd model ages old （1782～1918 Ma）．Source region composition dominated by Sandy Rock． Conclusions: These features consistently indicate that Qiling granite body is a typical Stypegranite of the Nanling region．It can be considered the Qiling granite is formed of the partial melting ancient crustal component in an tectonic environment that the pre-existing Dadongshan-Zhuguangshan fault zone has relived because of the Pacific plate subduction．