The Zhuxi W-Cu polymetallic ore deposit, located in the Jingdezhen of the Central Jiangnan belt in Jiangxi Province, is a skarn-type ore deposit in the Late Paleozoic carbonate basin on the Neoproterozoic basement. LA-ICP-MS Zircon U-Pb age, whole-rock major and trace elements of granite porphyry of this deposit were analyzed to discuss the emplacement ages and petrogenesis of this intrusion and the mineralization age of ore deposits. The LA-ICP-MS zircon U-Pb dating of granite porphyry shows that the crystallization age is about 150Ma. The major element analyses show that the rock is enriched in silica and alkali(with the average SiO2 76.57%, average（Na2O+ K2O） 5.43%), A/CNK>1.0, and can be classified as peraluminous. The rock is enriched in LREE and LILE, and depleted in HREE and HFSE in the primitive mantle normalized multi-element diagram, exhibiting obvious negative Eu anomalies and showing some characteristics of S-type granites in South China Low εHf(t) values -16.5~0.6 with Hf model ages 1.58~2.58Ga indicate that the Zhuxi granite porphyry was derived from partial melting of the Paleoproterozoic crust rocks and mantle materials could be involved in the magmatic sources. The large scale mineralization of the Zhuxi W-Cu polymetallic ore deposit are closely related to granite porphyry in the Zhuxi and may be contribute the mineralization material and force.