Controlled by the Cretaceous uplift of the Qilian Mountains, a series of continental basins were formed in the Hexi-Corridor area and its adjacent areas of Gansu Province, in which accumulated continental strata with the thickness of about one thousand meters. In these continental strata, depositional sequences that are made up of a particular succession of sedimentary facies could provide a typical pattern of continental sequences under the concept framework of the “unconventional system tract”, and are meaningful for the further understanding of the formation of the Tibetan Plateau and its impact of environment in Asia. The Hekou Group of the lower Cretaceous at the Shibalipu section in the Gulang County of Gansu Province, which is accumulated in the north-western margin of the Lanzhou Basin in the early Cretaceous, its stratigraphic features as well as sedimentological natures become the sedimentological response of the Cretaceous uplift of the Qilian Mountains and can further be summarized as following several aspects: Firstly, a set of course clastic rock system with the purple tonel constitutes the lower part of the Hekou Group, which can be subdivided into three depositional sequences, and the low accommodation system tract of the sequence is made up of the course clastic deposits belonging to the alluvial-fan and the braided river, the high accommodation system tract is made up of the fine-grained deposits of lacustrine. Secondly, a set of red beds constitutes the upper part of the Hekou Group, which can be subdivided into two depositional sequences, and the low accommodation system tract of the sequence is made up of the course clastic deposits belonging to the pluvial-fan and the braided river, the high accommodation system tract is made up of the fine-grained deposits of arid lacustrine with the development of eolian sand dunes. Thirdly, a sequence-stratigraphic succession that is changed upward to a set of red beds formed in the arid climate setting from a set of course calstic rock system with the purple tonel that is chiefly formed in the humid climate setting, especially for the development of eolian sand dunes in the red beds, is genetically related to the “rain shadow effect” resulted from the uplift process of the Qilian Mountains. Therefore, a particularly sequence-stratigraphic succession for the Hekou Group in the study area, which is characteristic of a sedimentary succession of both a composition of special sedimentary facies and their evolutionary succession, not only becomes an important substance record for the further understanding of the Cretaceous uplift of the Qilian Mountains but also provides another important record for the reconstruction of the pattern of the atmospheric circle in the East Asia.