The drill core of ZK06 in Gasikule Salt Lake，which was located at the southwest of the Qaidam Basin in Qinghai Province，was selected as the research object．Based on the pollen data，geochronology and uranium concentration in sediments，this paper discussed the relationship between uranium distribution and paleo environment. The results revealed that Gasikule Salt Lake undergo 6 times of saline deposition and 6 times of detrital deposit from 280ka．Paleo vegetation changed from veld to desert steppe，and the paleo climate changed from cool and mid wet to cold and dry. Uranium concentration in sediment was significantly correlated with total sporo pollen concentration, shrubs and artemisia. The uranium concentration in pollen zone was three times compare to saline deposits．Finally，the arid and cold climate both went against the uranium enrich in sediment, but the temperate and wet climate were adversely. Pollen assemblage characteristics maybe provide paleo vegetation and paleo climate evidences for uranium and others trace elements sediment in salt lake