There contained abundant uranium resources in the Cenozoic basins, western Yunnan,where 8 small-sized or medium-sized sandstone-type uranium deposits have been prospected ,and which is one of the important belts of sandstone-type uranium mineralization in China. Having collected and studied the data from 1200 drills, constructed 25 drills, writers drew up 66 rock-lithofacies-geochemical profiles, and studied the relations between the Cenozoic basins and sandstone-type uranium mineralization. It is considered that there exists two sorts of Cenozoic basins,they are different on sedimentary evolution ,volcanic activity and geographic view etc. , the metallogenic conditions of sandstone-type uranium deposits are also different. The advantaged basins for prospecting sandstone-type uranium deposits are those basins that developed regional isolatable water layer over the prospecting target layers, existed volcanic activity and deep incised landscape of low mountain-hill-river valley terraces in northern Tengchong area.