According to the analysis of the Paleozoic paleobiogeographic provinces of the eastern Qinling, this paper points out that in the Erlangping trough of the northern Qinling folded belt the Cambrian radiolaria and microphytoplankton belong to the South China province, the Ordovican cephalopods, gastropods and coral belong to the North China province and the Silurian coral to the South China province; spores of the Middle Devonian to Permian in the Shishuyuan trough are mainly discovered in the South China province; and the coral and crinoids in the Ganjianghe trough belong to the South China province. In the Xichuan shelf of the southern Qinling folded belt, Cambrian trilobites belong to the North and South China provinces, Ordovician conodonts, cephalopods evolved from the South China province to the North China province, and the Late Ordovician brachiopods, trilobites and coral are from the North China province, while the Early Silurian graptolite and the Middle Devonian coral, brachiopods and plant as well as the Early Carboniferous coral and fusulinids are all from the South China province, and the spores in the Nanwan trough belong to the South China province. On this basis the paleogeographical changing process during the Paleozoic in the eastern Qinling is discussed.