Apatite fission track chronology is a low temperature thermochronology based on the radiation damage effect of 238U spontaneous fission of apatite. The apatite seal temperature is low and sensitive to temperature change, and it can record important information such as the time, duration, distribution characteristics and activity rate of thermal events. The traditional external detector method (EDM) uses thermal neutron irradiation to generate induced fission track of apatite 235U, and then obtains the age of the fission track through correction calculation. The laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) method can directly analyze the content of 238U, which is convenient and fast. Electron probe microanalysis (EPMA) and Atomic force microscope (AFM) as auxiliary means can achieve more accurate fission track statistics. At present, the accuracy and comprehensiveness of the experimental methods, annealing dynamic models, and data interpretation are still insufficient. The integration of these processing elements with the geological evidence needs to be continuously upgraded. Nevertheless, the results of apatite fission track chronology and thermal evolution simulation have played a great role in determining the metallogenic age of hydrothermal deposits, dividing metallogenic stages, restricting the duration of hydrothermal mineralization, and quantifying the uplift and exhumation amounts of deposits. It has a broader development prospect and application space in determining the preservation and change law of deposit, predicting concealed deposit and ore body and so on.