The geochemical prospecting method and quantitative forecasting model of lead isotopes have been applied and popularized in exploring U, Cu, Au and PbZn deposits. In this paper, the method and model were introduced into the Ge’erke gold deposit in the Dashui ore field for buried orebodies prospecting. This paper focuses on twelve exploration lines of Ge’erke gold deposit, while calculates and forecasts a series of important parameters including ore buried depth limit (HL), ore buried parameter (R), buried resource reserves (QB) and concentration coefficient (K). The forecasting results indicate that the best potential area of buried orebodies prospecting is likely located in the west of study area, and the potential decreases from west to east. Finally, the forecasting results are compared with the actual production data and information of the nearly eight years after forecasting. The comparison results show that the forecasting model and result are right, and successfully guiding buried orebodies prospecting; a significant breakthrough of buried orebodies prospecting are made in the west of study area, while the buried resource reserve of Au2 gold orebody can achieve the forecasting resource reserves of the whole study area; the buried resource reserves (of Au111 and Au37 gold orebodies) of the middle and east areas are also greater than previously thought; the actual production practices further improve the potential of buried orebodies. This paper not only provides a new successful instance of lead isotopes exploration to buried orebodies prospecting, but also supplements and improves the quantitative forecasting model of lead isotopes.