The Shangxu orogenic gold deposit locates to the south of the middle part of the Bangong Nujiang suture zone in northern Tibet.Four stages of mineralization were identified, which are quartz stage (S1), quartz pyrite stage (S2), quartz polysulfide stage (S3) and carbonate stage (S4).Furthermore, the precipitation of gold mainly occurs in S2 and S3.The wall rocks of the deposit are the Middle Lower Jurassic metamorphic flysh Mugagangri Group.The sulfides in S3 has a narrow δ34S range of -4.5‰ to -1.0‰ with an average of -3.1‰, which is consistent with the δ34S of pyrite from the wall rocks, indicating sulfur mainly derived from the metamorphic flysh Mugagangri Group.The δ34S values of S3 satisfy δ34SGn <δ34SSp，representing the outcome of sulfur isotopic thermodynamic equilibrium fractionation; meantime，the temperature is 197 ℃ according to sphalerite galena sulfur isotopic thermodynamic equilibrium.Three samples from S3 yield 206Pb/204Pb values of 18.35~18.69 and 207Pb/204Pb values of 15.64~15.70, and 208Pb/204Pb values of 38.57~38.98; theμvalues vary from 955 to 963, while the ω values vary from 37.75 to 38.15, indicating that the lead source was highly mature and derived from the upper crust, maybe including the contribution of melange in orogenic belts.