The study of element enrichment mechanism is the basis for reproducing the metallogenic process and determining the metallogenic mechanism, which is helpful to deepen the understanding of ore deposits and provide theoretical basis for prospecting. This paper reviews the research and application of the migration and precipitation mechanisms of Pb and Zn elements in recent years, including three migration and precipitation models, four fluid-driven models of lead and zinc, and the forms and mechanisms of Pb and Zn migration and precipitation. At the same time, the development of domestic HPHT(high pressure and high temperature) experiments and four kinds of HPHT simulation experiment methods are introduced. This paper introduces four simulation methods and their research status: ① computer simulation experiment; ② autoclave experiment; ③ hydrothermal diamond cavity-laser Raman experiment; ④ Fused capillary silicon tube—laser Raman experiment. Gradually from closed equilibrium—still to (semi) open—unequilibrium—flow and hardening analysis is mainly based on field observation, which should be the development direction of high temperature and high pressure experiments.On the basis of geological characteristics, through HPHT computer simulation experiments and the diagenesis and mineralization simulation experiments describe the mineralization process finely and reveal the element enrichment mechanism.It is not only an effective means to solve practical geological problem, but also a direction that has been striving for a long time.