Terrestrial in situ cosmogenic nuclides(TCN) exposure dating method is one of the most used methods for Quaternary geomorphological dating research, but due to the influence of inherited nuclides and erosion, the dating results are difficult to reflect the real exposure age of the landform. Using the cosmogenic nuclide concentration of samples at different depths can comprehensively determine the exposure age, erosion rate and inherited nuclides of the geomorphology at the same time, effectively compensating for this shortcoming. The cosmogenic nuclide depth profile model based on the Monte Carlo method (referred to as the Monte Carlo depth profile model) is one of the most used models, and there are few domestic studies, which greatly limits the wide application of this method. This review will explain the principle of Monte Carlo depth profile model and its application in various landforms such as glacial landforms, river terraces, alluvial fans, etc., and introduce several other calculation modes such as the rejuvenation of depth profile model, unsteady state model and linear inversion model. This article will also discuss the field sampling method of depth profile dating technology, in order to be widely used in Quaternary geomorphology and chronology research.