Taoyuan uranium deposit is located in the Wuyishan uranium metallogenic belt in the south China uranium metallogenic province,but the genesis of mineral deposit and the physical and chemical environment of mineralization have not been studied in depth.Geochemical characteristics of pyrite can often effectively reflect the geochemical environment at the time of formation.Pyrite and pitchblende are closely related in Taoyuan uranium deposit,northeastern Guangdong.Methods: This paper uses LA-ICP-MS testing technology to systematically analyze the major and trace elements of pyrite in the Taoyuan deposit.Results: The analytical results indicate that：①w(Fe)of pyrite are 41.64%~49.39% with the average of 45.83%,whereas its w(S)are 50.56%~57.62% with the average of 53.73%.The w(Fe)/w(S) is 0.73~0.98 the average of 0.85,indicating that its formation environment is a relatively closed geochemical environment with a weak iron deficiency and relatively rich sulfur;② Si, Na, Al, K, Ca, Cr, Co, Ni, Ti, Cu, Ge, As, Se, Bi, Pb and other trace elements are relatively enriched in pyrite;③There is no obvious linear relationship between most of the trace elements and the main elements Fe and S,indicating that the geochemical behavior of these trace elements is affected by other factors in addition to the isomorphic factors during the formation of pyrite.Conclusions: ① The ore-forming element U is positively correlated with some trace elements.The high content of Na,Ti and other elements indicates that the pyrite,which is closely related to uranium minerals in space,was formed in the alkaline hydrothermal alteration stage at the early stage of mineralization rather than the mineralization stage;② The micro- cracks within the pyrite are developed,and uranium minerals are easy to enter during the mineralization period,which causes the increase of uranium deposit amount near the cracks.The accompanying high content of as indicates that the pyrite was formed in a medium—low temperature hydrothermal environment;③ Pyrite provided reduction for uranium mineralization.