Objectives: Yangtze River basin is the southern boundary of dust and loess deposition in China. Wushan Loess distributed along the Three Gorges valley in Yangtze River is the representative loess profile in Yangtze River basin and has crucial scientific significance. It is significant not only to the supplement distribution region of loess, but also to the comparison with the north loess.Methods: Based on detailed field observation of Wushan loess profile in Shazhenxi section, Zigui, Hubei province, we have studied its features of petrology, stratigraphic structure. The division of the Wushan loess was initially proposed and comparison with the north loess was discussed. Results: Previous studies of the Wuhan Loess focus on the specific issue in a individual section in Wushan County, and the overall understanding of stratigraphic characteristics and Loess—paleosol sequence characteristics of Wushan Loess is still lacking, which has become a basic geological problem and seriously restrict its further development. In this paper, stratigraphic division of the Wushan Loess was carried out initially and comparison with the northern loess was performed according to the representative and integrated loess profile in Shazhenxi, Zigui County. The result showed that Wushan Loess has 4 layers of loess, 2 layers of caliche nodules and 1 paleosol layer, which were roughly equivalent to the top (L1—L2) of Malan loess and Lishi loess in the Loess Plateau. 4 layers of loess correspond to the L1-1、L1-3、L1-5 and L2 respectively in Weinan Loess Profile and 2 layers of caliche nodules correspond to the L1-2 and L1-4 respectively, and the paleosol correspond to S1. Conclusions: Comparation with the northern loess, the loess of Wushan Loess was darker and slightly red in color and the paleosol had more intense pedogenesis, which may be ascribed to different climate environment that Wushan Loess distributed in the south region of the Summer Monsoon control with stronger weathering.