Objectives: Frequent floods have occurred in the middle reaches of the Yangtze River in recent years, and the Wuhan Section is also the focus of flood protection in this area. Thus, it is of great significance to carry out the study on the paleoflood of the Yangtze River in Wuhan area so as to prolong the record of the paleoflood and forecast the flood. Methods: In this paper, the borehole SK10 of sink river valley lake in Wuhan area is selected as the research object. The stratigraphic age is determined by using AMS 14C dating technique. Through the determination and analysis of grain size and geochemical elements, a set of identification indexes for the paleoflood frequent occurrence period in Wuhan Section of the Yangtze River is established to study the paleoflood period in this section during 4. 5~2. 5 ka BP Results: Research shows: ①Based on the distribution relationship between the Houhu Lake and the Yangtze River, grain size indexes（P95, sand content, average grain size, clay/silt, (coarse silt+sand)/clay）and geochemical indexes（Na2O, Al2O3, Fe2O3, Zr/Rb, Rb/Sr）were selected as the identification indices for the paleoflood frequent occurrence in the borehole sediments, which have better indication for the paleoflood frequent occurrence period in Wuhan area. ②Frequent occurrence of paleofloods identified by indicators are about 2608±30 a BP, 2814±35 a BP, 3094±35 a BP, 3577±35 a BP, 3830±35 a BP, 3939±35 a BP, 4084±35 a BP, 4193±35 a BP, 4391±35 a BP, which are basically consistent with the records of several floods during 4.5~2.5 ka BP in the literature. Conclusions: The method of multi- indexes analysis has been successfully applied to Wuhan Area for paleoflood sediments identification, providing some new evidences for paleoflood frequent period in Wuhan Section of the Yangtze River.