The Junggar Basin, located in the north of Xinjiang, is one of the most important basins producing multienergy resources. On the basic study of basement structure, Mesozoic—Cenozoic tectonic evolution, sedimentary formation and epigenetic alteration, Umetallogenic characteristics have been analyzed and the types of Umineralization also been divided in this paper. Moreover, Geological models in different basin section are established. And the direction of resource breakthrough is discussed on the whole view of the basin. The basin basement is benefited for Umineralization and the general potential conditions of Umineralization are favourable . Interlayer oxidation zone type uranium deposit should lay stress on prospecting orientation in the whole basin. The most favorable prospecting formation are the Lower—Middle Jurassic strata, and the beneficial positions lie in the the eastern of Junggar Basin, following in the western area and the Heshituoluogai depression. Oilcovered type Umineralization also has a greater potential for prospecting in the west part of Junggar basin while Savoy bucchi type Udeposit in the southern margin being as the important direction for prospecting.