Wanyangshan batholith is an important part of Caledonian magmatism in south China. Though some work have been performed to reveal petrology, geochemistry, UPb dating and tectonic setting of the batholith, but lack of work on tectonic setting of Caledonian granitoids. We discuss tectonic setting of Caledonian granitoids and provide new data for early Late Paleozoic granite and crustal evolution in south China.Methods:We apply methods including zircon LAICPMS UPb dating, main elements, trace elements, rare earth elements and Sr, Nd isotopic analysis and testing. We analyze the interior structures of zircons by the CL technology and insitu zircon UPb dating of a biotite twomica monzogranite sample. For main elements analysis and testing, we apply burning method for Si summation, volumetric method for Al and Fe2+, spectrophotometric method for Fe3+, Ti and P, atomic absorption spectrometry for K, Na, Ca, Mg and Mn. Trace elements and rare earth elements have been tested on the X series Thermo 2 type inductively coupled plasma mass spectrometry. Sr and Nd isotope analysis has been performed on the MAT261 multi receiver mass spectrometer.Results:We obtained the 16 points of zircon 206Pb/238U weighted average ages of （446.0±3.4）Ma(MSWD= 0.15, 95％ confidence degree), suggesting crystallization age of the batholith. The result indicates it formed during late Ordovician to Early Silurian the Southern China Caledonian magmatism. Geochemical analyses showed that: the Wanyangshan batholith has a SiO2 content of 65.91 to 73.35％, an average K2O content of 4.20％,(Na2O+K2O) content of 5.90 to 7.88％.the average of K2O/Na2O, Al2O3 and ASI are 1.64, 13.81％ and 1.09％. Which indicates granitic pluton is highK calcalkaline peraluminous. The contents of Rb, (Th+U), (Nb+La+Ce), Nd,(Zr+Hf+Sm) and (Y+Yb+Lu) are relatively higher and the granite intrusion has moderate ∑REE (159.71×10-6~262.78×10-6). It is enriched in LREE and depleted in HREE(LREE/HREE=6.16~10.01), (La/Yb)N=6.37~12.17,with obvious negative Eu anomaly (δEu = 0.30~0.59).The Wanyangshan granite has a range of initial strontium from 0.71223 to 0.72509, and a range of εSr(t) from 117.5 to 299.9, εNd (t) ranges from -9.39 to -7.30, with the depleted mantle model age of 1.77~1.95 Ga.Conclusions:Those methods above have been successfully applied to formation mechanism of Caledonian Wanyangshan batholith, providing some new evidences for understanding the tectonic setting of Southern China Caledonian granites.Acknowledgements: This study was financially supported by the Chinese Geological Surveey(No. 1212011120804, No.12120114084501 and No.12120114020701). We would like to express our thanks to Xia Jinlong from Wuhan Center of China Geological Survey for explanation of isotopic dating. We would also like to exprese our thanks to reviewers and editors for valuable advice on this paper.