Douzhashan granite is an important uranium bearing granite in Miaoershan uranium ore field, northeastern Guangxi. Based on mineralogical study, chlorites can be classified as two types: ripidolite and diabantite, and the alteration of U riched accessory minerals is closely correlated to the ripidolite which formed in higher temperature. The major hosted minerals for uranium are uraninite, zircon, monazite, xenotime and thorite coffinite. Among these U riched minerals, uraninite is generally acknowledged as uranium resource mineral, but if the other U riched minerals are uranium resource minerals depend on their occurrence and alteration. Most zircons are unaltered and still preserved U in internal structure，so zircon is not a uranium resource mineral. In near ripidolite, monazite and xenotime often have various degrees of alteration. The hydrothermal alteration not only made the uranium liberated from the altered accessory minerals into fluid, but also changed the occurrence of thorite coffinite from included in xenotime to secondary apatite. So, uraninite, altered monazite and xenotime, thorite coffinite included in secondary apatite are uranium resource minerals in Douzhashan uranium bearing granite.