This paper analyzes the changes of global uranium exploration expenditures, uranium resources policy and regional distribution pattern since the 2008 financial crisis, and summarizes the main progress of global uranium exploration in this period. It is estimated that the exploration investment of global uranium resources will gradually increase in the next decade. It is considered that the first target deposit type of uranium exploration is sandstone type and unconformity- related type, followed by calcrete type, intrusive rock type, breccia complex type and quartz—pebble conglomerate type. Canada, Australia, Kazakhstan, Namibia, Niger, South Africa, China, Russia, the United States, Mongolia, India will continue to be the key regions of global uranium exploration; South America may become a hot spot for uranium exploration. It is difficult to revive uranium exploration and exploitation in Europe (except Russia). New breakthroughs may be made in the prospecting for in- situ leaching sandstone type uranium deposits in Canada and southern Africa.