The porphyry copper belt in Sonora, northern Mexico, is an extension of the “large cluster” of North American porphyry copper ore concentration areas in Mexico, one of the world’s important copper metallogenic provinces. Porphyry copper deposits are mainly distributed along the Laramide magmatic arc. During the Laramide (80~40 Ma) orogeny, due to the reduction of the subduction angle of the Farallon plate to the North American plate, the magmatic activity center gradually moved eastward, forming three magmatic activities of 76~70 Ma, 63~57 Ma and 46~40 Ma. During the peak period, the magma activity of 63~57 Ma was the largest. Through the comparative study on the metallogenic age of the existing deposits in the area, the time limit of magmatic activity and the distribution concentration of the deposits, it is found that the peak period of porphyry copper metallization is mainly concentrated in the period of 63~56 Ma. By combing the metallogenic characteristics of typical deposits and comprehensive analysis of regional magmatism, it is believed that the Laramide orogeny is the main geological process for the formation of huge copper and molybdenum enrichment in northern Mexico.