The Shihongtan uranium deposit in Xinjiang is an interlayer oxidized zone type sandstone uranium deposit, which was found a few years ago in China. The deposit is located in the Aidinghu clinoform belt, west of the Turpan depression in the Turpan-Hami basin. The ore-hosting bed is coal-bearing detrital rocks of braided meandering stream facies in the Middle Jurassic Xishanyao formation. The orebodies are controlled strictly by the leading edges of interlayer oxidized zones, developed in fluvial sand bodies. The orebodies are curly or tabular in form. The ore-bearing rocks are mainly grey-dark grey, loose and sub-loose, fine-coarse feldspathic quartz sandstone. Uranium occurs in an adsorption manner. The main ore-forming age given by the whole-rock lead isotope assaying is 24 Ma. The authors consider that the genetic mechanism of the uranium deposit is as follows. After the Late Jurassic, interlayer oxidized zones were fully developed in a long-term xerothermic condition and highly oxygenated water moved forward continuously in sand bodies of uranium-rich strata. As a sequence, uranium was precipitated and enriched in geochemical barriers enriched in reduction agents to form such a uranium ore deposit