The Wuzur′enbulage intrusion is located in the eastern section of South Tianshan Orogenic Belt(STOB), which is of great significance for studying the closure time of the Paleozoic South Tianshan Ocean and the tectonic evolution of STOB. In this paper, we report new zircon U-Pb age and geochemical of the Wuzur′enbulage intrusion in the eastern section of south Tianshan Mountains. Methods: On the basis of field investigation, according to the zircon U-Pb age, combined with geochemical characteristics.Results:The zircon U- Pb dating results show that the two ages of granite are 291.2 ± 2.9Ma and 284.9±3.7 Ma，indicating that the Wuzur′enbulage intrusion was formed in the Early Permian. They are characterized by high Si，rich in Al and alkali and low content of Ca, Mg, Fe, Ti and P，belong to high- potassium calc-alkaline I-type granite. They are enriched in LILEs and LREEs, depleted in HFSEs (e.g., Nb, Ta, P, Ti), medium- negative Eu anomalies (δEu = 0.27~0.87), and predominately negative Sr, Ba anomalies.Conclusions：The Wuzur′enbulage intrusion was emplaced in a post- collisional environment，indicating that the eastern section of South Tianshan Ocean was closed at least in the Early Permian, and STOB evolved from syn- collisional tectonic environment to post-collisional tectonic environment in the Early Permian.