As a type of clean and renewable resource, geothermal energy has been widely utilized in power generation and heating. Radiogenic heat is a primary source for geothermal energy in earth. The research on radiogenic geothermal energy has been focused on its application in detecting and evaluating potential for dry hot rock. However, as vital radioactive source, the research about the genetic relationship between hydrothermal uranium deposits and geothermal energy is poor. This paper collected and sorted out a large number of domestic and foreign literature as well as related materials to enhance the research about the genetic relationship between geothermal energy and hydrothermal uranium deposits. Based on the research progress and existing problems, method to solve this issue is put forward. Through this study, a new thought and method can be provided for studying the genetic relationship of geothermal energy and hydrothermal uranium deposits and certain theoretical basis could be supplied for “geothermal energy—ore jointly exploring”.