Objectives:The distribution of selenium in different regions and different layers of soil is uneven. The development of different natural selenium- enriched foods based on local selenium- enriched soil clues is an important direction for the development of local characteristic agricultural research. According to the data of 1∶250000 target geochemical surveys in Yunnan Province and 1∶50000 four regional geological surveys in Yunnan, the surface soil in Yunnan Province is relatively lean in selenium, but in the Yimen Pujia Village—Tongchang township—Xishan Village—Shizishan—Lufeng tuguan town,There are about 400 km2 of selenium- enriched soil in the local low mountain . Results: The average selenium content of soil is 0.54 μg/g, and the selenium content of local soil is 136 μg/g. The profiles show that the selenium element exhibits the phenomenon of surface aggregation. Selenium is larger than the deep soil in the topsoil, while the selenium content in the deep soil is larger than that in the parent rock. Conclusions:The selenite content of different bedrocks shows carbonaceous slate. It is larger than argillaceous slate and larger than silty slate, which is positively correlated with carbonaceous, clayey and muddy. According to this clue, a large number of natural selenium- enriched wild mushrooms and vegetables were newly discovered in the local area. Preliminary studies have shown that the formation of local selenium- enriched soil is related to the specific geological background, while the soil environment for producing natural selenium- enriched wild mushrooms and vegetables is relatively superior.