This paper summarizes the characteristics of Middle Jurassic Toutunher formation and Xishanyao Formation of interlayer oxidation zone and uranium mineralization in Kamust area, reconstructs The uranium metallogenic model by using interlayer oxidation zone sandstone uranium deposit metallogenic theory. It is believed that the uranium mineralization and anomaly are consistent with the theory of interlayer oxidation zone, controled by Interlayer oxidation zone and unconformity, and Accorded to the interlayer oxidation zone sandstone type uranium metallogenic regularity. It is pointed out that the purpose of uranium deposits in the area is mainly in the Middle Jurassic Toutunhe formation, and the second one is Xishanyao formation, The main types of ore deposits is the interlayer oxidation zone sandstone type, followed the unconformity type sandstone type and the coal rock type. It is clear that the prospecting direction in the future and this paper can provide reference for the future exploration of uranium resources in Junggar basin.