Because of the strong uplift of the Qilian Mountains since late Cenozoic, the drainage basins that derived from the mountain have undergone strong tectonic deformation, so the typical geomorphology characteristics of these drainage basins may indicate the strong tectonic movement in the region. Controlled by north Qilian Mountains fault and Qilian—Haiyuan fault, the eastern margin of Qilian Mountains which developed Gulang thrust nappe have undergone strong tectonic deformation and formed unique geomorphological characteristics, previous researchers studied the study region from the geological and geophysical view, while little concern was payed to the eastern Qilian Mountain from the geomorphological view. Methods:Based on ArcGIS spatial analysis, this study takes advantage of Digital Elevation Model (DEM) to extract macro landscape factors (such as Hypsometric Integral and Swath profiles) in the study area and combines rainfall and lithologic data to give systematic analysis to its geological significances. Results:The study shows it is the tectonic movement of the active fault but the lithologic factors and precipitation conditions that has strongly influenced on the regional geomorphic evolution; in addition, controlled by Huangcheng—Shuangta fault, Lenglongling fault and Lianhuaqiao fault, Gulang thrust nappe brings out high HI value, Hexibao—Sidaoshan fault, which lies on the east side of the Longshou hill, shows high HI value on its south side and relatively low HI value on its north side. Furthermore, the seven swath profiles indicated that the macrotopography is largely controlled the activities of the range—front faults.Conclusions:The results show that all the macro geomorphologic factors indicate that the eastern margin of the Qilian Mountains, even Xizang(Tibet) Plateau has been extending northward, and this study provide the geomorphic evidence that the north Qilian Mountains fault has extended into Hexi Corridor.