Gaoling quartz-vein type tungsten deposit is located in southern margin of the Miao'ershan—Yuechengling batholith. The granitic rocks closely associated with tungsten mineralization can be divided into two facies according to the contents of phenocrysts: medium- to fine-grained porphyritic two-mica granite, and medium- to fine-grained two-mica granite. Whole rock chemical analyses indicate that the granitic rocks have high SiO2 and are metaluminous to slightly peraluminous, which belong to typical highly fractionated S-type granites. They have relatively low total REE contents and are enriched in LREE, Cs, Rb, Th, U, Pb, depleted in HREE, Ba, Sr, Ti. In-situ LA-ICP-MS zircon U-Pb chronology indicates that the granitic pluton was emplaced at 224.9±1.4 to 220.2±1.6 Ma. Furthermore, we analyzed the Sm-Nd isotopic compostions in scheelite concentrates and obtained a Sm-Nd isochron age of 212±20 Ma (MSWD = 0.52). The result suggests that the tungsten mineralization in Gaoling depositis the response of the Triassic tungsten mineralization event in the western Nanling Range. The detailed observations of ore minerals under optical microscope and EPMA show the Gaoling tungsten deposit was formed in two mineralization stages: (1) wolframite—scheelite—quartz vein stage; (2) scheelite (wolframite)—sulfide—quartz vein stage. εNd values of the scheelite concentrates range from -8.9 to -9.4，which is correspond with the crustal origin of typical highly fractionated S-type granite and indicates that the parental granite was formed by the partial melting of the crustal basements.