The Daotuo manganese deposit is an all buried large manganese deposit that had been newly discovered during the integrated exploration in Guizhou. The manganese bearing rock series characterized by layered, stratoid or lenticular structure occured in the “black shale” at the bottom of the First Member of the Datangpo Formation, Nanhua System， Neoproterozoic. In this paper, geochemical characteristics of major and trace elements of the manganese bearing rock series were analyzed. Some geochemical parameters such as the ratios of V/(V+Ni), V/Cr and Ce/La, as well as the enrichment of redox sensitive elements(U, V, Ni and Mo) of the manganese bearing rock series indicate that the deposit was formed a hypoxia environment. In addition, enrichment of elements like As, Mo, Ag and Sb, and the ratios of Al/(Al+Fe+Mn), (Fe+Mn)/Ti, Co/Zn together show typical hydrothermal sedimentary characteristics; and, the diagrams of (Cu+Ni+Co) 10—Fe—Mn and Co/Zn—(Cu+Ni+Co) also show hydrothermal sedimentary characteristics; implying that hydrothermal activities played a vital role in the enrichment of manganese and the formation of the deposit. Furthermore, the ratios of Al2O3/(Al2O3+Fe2O3), Al/(Al+Fe), Al/(A1+Fe+Mn) and (La/Ce)N and the diagrams of K2O/Na2O—SiO2 and La/Ce—Al2O3/(Al2O3+Fe2O3) all suggest that the manganese bearing rock serious may have been formed at a passive continental margin.