In this paper，a prediciton model based on fuzzy multi attribute decide making has been posed and application in the Yushigou area, Qilian Mountain, Qinghai Province. Based on geological background and metallogeny of the Yushigou area, mineralizing information is extracted. Then use GIS to correlate and analylize multi-source information for establishing mineralization prediction index of copper-zinc ore. Finally, a eclectic fuzzy multi-attribute decision-making method is used in ore-controlling indicators for integration and decision-making. Compromised fuzzy multiple attribute decision making method is established by fuzzy positive and negative ideal value of each predictor, after which measure tools of weighted Euclidean distance are used to calculate the distance between the evaluation unit and the fuzzy positive or negative ideal, membership degree of each evaluation unit to fuzzy positive ideal is then calculated to measure the metallogenic favourability degree. The result is that 8 copper and zinc deposits has been prospected. Compared with the results obtained by fuzzy comprehensive evaluation model, the result is more convergence and centralized, more accurate positioning, and more consistent with the engineering verification with the actual situation. The model provides a new way for the realization of a low level of new mines forecast. Metallogenic prospect area is located at the junction of faults and secondary fracture and indicates that the strong fracture development convergence zone has good ore prospects.