Qimantage tectonic—magamatic belt in East Kunlun Mountains develops a large number of granitoids associated with the caledonian orogency. Researching these can provide new informations for the tectonic evolution of Qimantage in Early Paleozoic, and also has great significances for investigating the geodynamic evolution characteristics of the whole East Kunlun orogenic belt. In this paper, writers report the new zircon U Pb ages and geochemical datas of the biotite monzogranite in East Nalinggele River and the potash feldspar granite in Wulanwuzhuer, and discussed the petrogenesis and tectonic significance of Late Silurian to Early Devonian granitoids in studied area. The LA ICP MS zircon U Pb ages of the biotite monzogranite and the potash feldspar granite are 4206 ±26Ma and 4212 ±19Ma, respectively. Late Silurian to Early Devonian granitoids in studied area belong to high K calc alkaline metaluminous to peraluminous rocks，with REE patterns displaying enriched LREE，flat HREE and moderate negative Eu anomalities, and trace elements showing relative enrichment of large iron lithophile elements Rb,Th and depletement of high field strength elements Nb,Sr,P,Ti; the tectonic setting is post collision, and the petrogenetic type gives priority to high K calc alkaline I type granites, meanwhile, the study area exposures some S type granites. It is inferred that tectonic regime transformation from compressive tectonic setting of syn collision to stretching tectonic setting of post collision produces the granites having some traits of A type granites，high K calc alkaline I type granites and peraluminous granites.