Leaf Margin Analysis (LMA) is a method which bases on the relationship between the proportion of woody dicotyledonous species with untoothed leaves (P) and mean annual temperature (MAT) to quantitatively estimate paleotemperatures from fossil leaf floras. In recent years, LMA is widely used for paleoclimatic reconstructions of Cenozoic leaf floras. Even with the high correlation between P and MAT, studies from different regions indicate that this method shows regional constraints. In recent work, a new Chinese LMA model was proposed based on 50 samples from humid to mesic forests in China. This new Chinese LMA model was applied to reconstruct paleoclimates of Chinese Cenozoic leaf floras in this paper. Estimated MATs from this new model are similar to these from other different methods in former studies. Therefore, this new LMA model from China, other than the widely used East Asian LMA model, is more properly applied to paleoclimatic reconstructions of Chinese Cenozoic leaf floras. In order to improve the accuracy of paleoclimatic reconstructions, more work is need by the following aspects: i.e., regional constraints of LMA, accurate definition of entire leaves, available climate data, taphonomic process, and the mechanisms of leaf physiognomy in response to the surrounding environment.