The Earth had experienced many events since it was formed, which include the occurrence of the earliest life, atmospheric oxygenation, the snowball Earth and several times of mass extinction and rejuvenation. Stable isotopic analysis of certain elements in the Earth can track the life evolution and concurrent environmental change. It provides an ideal tool for geological event investigation. Carbon isotopic fractionation records the beginning of earlier life, while independent mass fractionation of sulphur isotopes records the dramatic changes of the oxygen content in the air. Whenever the mass extinctions occur in the Phanerozoic, carbon isotopic values always show a negative shift.