The Qinling Mountains are an important boundary of geology, geography and zoology in China, and its large-amplitude uplift has been one of the most striking geological events in eastern China since the Late Mesozoic. The study of teh uplift stages and amplitudes of the Qinling Mountains is helpful to understand profoundly such important problems as the persent climate, geology, geography and zoology of China. The paper analyzes the uplift amplitudes of the Qinling Mountains in various periods since the Late Mesozoic on the basis of the distribution and characters of fossils in the area as well as the comparison with contemporaneous biotas of the north and the south of China. Qinling became land and was uplifted at the end of the Triassic, but the uplift amplitude was limited. In the Cretaceous and Paleocene, the topographic relief was not sharp. During the middle and late Paleogence an intense uplift occurred in Qinling Mountains, and the sharp relief had an obvious obstructive effect on the migration of animals. The subsequent planation caused animals in the Qinling Mountains to maintain a good intercourse with those out of the mountains in the Neogene. The Qinling Mountains once again displayed the feature of vertical movement in the terminal Early Pleistocene. The uplift amplitudes at the east and west ends of the Qinling Mountains were obviously not the same because of the influence of the uplift of the Qinghai-Tibet Plateau.