The autocorrelation filtering method can be applied to oil and gas exploration, and can provide a reliable and accurate research method for the favorable local structure of oil and gas reservoirs in other oil and gas exploration areas, so as to achieve the effect of assisting oil and gas exploration.Methods: On the basis of discussing the theory of autocorrelation filtering method, through experiments on various theoretical models, by analyzing the advantages of the experimental results of the method, and taking the gravity data of a region in China as an example, the autocorrelation filtering calculation of the gravity data in this region is carried out.Results:The results suppress the influence of the regional field, extract the local weak anomaly related to the reservoir, and verify with the Bouguer gravity anomaly, vertical derivative and residual anomaly, and obtain good application results.Conclusions: The autocorrelation filtering method is used to process the gravity anomaly data, suppress the influence of the regional field, highlight the local weak anomaly, not only extract the meaningful anomaly from the superposition field, but also the anomaly range is closer to the actual boundary of the source body than the original anomaly