Abstract:Objectives: Longshan County of Hunan Province, as one of the important lily production bases in China, has a certain degree of cadmium (Cd) pollution risk in its soil. Meanwhile, lily, as both an edible and medicinal plant, has inconsistent quality and safety standards for food and drug. Therefore, it is of great significance to propose safety zoning of lily planting regions in Longshan County. Methods: 326 samples of surface soil and 70 samples of lily (corresponding to rhizosphere soil samples), which were collected from cultivated land in Longshan County, were analyzed in terms of the Cd contents of soil and lily, as well as oxides, organic matter, pH and other indicators of soil. On this basis, the influencing factors of Cd bioavailability were explored. Accordingly, the prediction model of Cd bioconcentration factors of lily was established to predict the Cd content of lily in cultivated land, and the safety zoning and suggestions for lily planting regions were put forward by combining with the data from geochemical survey of land quality. Results:The results show that the soil is at the risk of Cd pollution and there are some quality and safety problems with lily in study area. The bioavailability of Cd is jointly affected by the CaO, S, P, K2O contents and pH value of soil in study area. Compared with the multiple linear regression model, the random forest model can better predict the Cd bioconcentration factors of lily. The safety zoning of lily planting regions show that the edible lily priority planting regions, the medicinal lily priority planting regions, the medicinal lily secondary planting regions, and the structural adjustment planting regions account for 1.49%, 92.71%, 2.88% and 2.92% in study area, respectively, and it is suggested to energetically develop agricultural products of medicinal lily. Conclusions: The study results effectively connect the safe utilization of Cd- contaminated cultivated land with the quality and safety of the edible and medicinal agricultural products, enhance the method of the safe utilization of contaminated cultivated land and provide scientific supports for promoting the lily industry development of Longshan County.